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Hypertrophic cardiomyopathy (HCM) is a genetically determined disease that commonly results in obstruction of the left ventricular outflow tract (LVOT), which can produce chest discomfort, dyspnea, fatigue, and syncope. This topic discusses the management of patients with HCM and symptoms attributable to LVOT obstruction.Furthermore, depending on thrombus morphology and the time of follow-up, LV thrombus has in the past been associated with up to a 22% risk of embolization 20–23 and a 37% risk of major adverse cardiovascular events (MACEs). 17.
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Herein we review the conventional assessment of LV systolic function and examine the role of speckle-tracking echocardiography (STE), a new method to assess LV function. We also highlight the role of STE in the assessment and management of cardiac and noncardiac disease, including detection of subclinical LV dysfunction.
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