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2 · large core stroke trials
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We established a collaborative group to pool patient-level data from these trials: .Little more than 20 years ago, stroke was widely regarded as an untreatable .
Distribution of scores at 90 days in the intervention and control groups in the .
The trial was based on the best available evidence at the time, which indicated .The treatment approach for acute ischaemic stroke is straightforward: restore blood .
The HERMES trial is an international, multicentre, parallel group, randomized, double-blind, . Methods: We formed the HERMES collaboration to pool patient-level data from five trials (MR CLEAN, ESCAPE, REVASCAT, SWIFT PRIME, .
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The study investigators established the Highly Effective Reperfusion Evaluated .
Goyal M, Menon BK, van Zwam WH, et al; HERMES Collaborators. Endovascular . In this trial, endovascular thrombectomy for ischemic stroke 6 to 16 hours after a patient was last known to be well plus standard medical therapy resulted in better 90-day functional outcomes .
We performed a prospective, randomized, open-label, adaptive, international .
Michael D Hill, Tudor G Jovin, for the HERMES collaborators Summary Background In 2015, .
large core thrombectomy trials
We analyzed data from the highly effective reperfusion evaluated in multiple .
We aimed to assess whether the treatment effect of EVT on improved . We established a collaborative group to pool patient-level data from these trials: the Highly Effective Reperfusion evaluated in Multiple Endovascular Stroke Trials (HERMES) collaboration. Differences from the TREAT meta-analysis protocol 9 include sampling frame and the primary research question.
Methods: We formed the HERMES collaboration to pool patient-level data from five trials (MR CLEAN, ESCAPE, REVASCAT, SWIFT PRIME, and EXTEND IA) done between December, 2010, and December, 2014. In these trials, patients with acute ischaemic stroke caused by occlusion of the proximal anterior artery circulation were randomly assigned to .The HERMES trial is an international, multicentre, parallel group, randomized, double-blind, study in patients with HFpEF and HFmrEF, evaluating the effect of ziltivekimab 15mg compared with placebo, given once a month, in addition to standard care, on the primary composite outcome of time to first occurrence of cardiovascular death, heart .
The study investigators established the Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials (HERMES) collaboration to undertake meta-analysis of pooled individual patient data.Goyal M, Menon BK, van Zwam WH, et al; HERMES Collaborators. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials.
In this trial, endovascular thrombectomy for ischemic stroke 6 to 16 hours after a patient was last known to be well plus standard medical therapy resulted in better 90-day functional outcomes . We performed a prospective, randomized, open-label, adaptive, international trial involving patients with stroke due to occlusion of the internal carotid artery or the first segment of the middle.Michael D Hill, Tudor G Jovin, for the HERMES collaborators Summary Background In 2015, fi ve randomised trials showed effi cacy of endovascular thrombectomy over standard medical care in patients with acute ischaemic stroke caused by . We analyzed data from the highly effective reperfusion evaluated in multiple endovascular stroke trials (HERMES) collaboration, which performed an individual patient data meta‐analysis of 7 randomized controlled trials conducted between 2010 and 2017 assessing the benefit of EVT compared to medical management in patients with anterior .
large core stroke trials
We used individual patient data from 6 randomized controlled trials within the HERMES (Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials) collaboration to validate the original model. We established a collaborative group to pool patient-level data from these trials: the Highly Effective Reperfusion evaluated in Multiple Endovascular Stroke Trials (HERMES) collaboration. Differences from the TREAT meta-analysis protocol 9 include sampling frame and the primary research question.
Methods: We formed the HERMES collaboration to pool patient-level data from five trials (MR CLEAN, ESCAPE, REVASCAT, SWIFT PRIME, and EXTEND IA) done between December, 2010, and December, 2014. In these trials, patients with acute ischaemic stroke caused by occlusion of the proximal anterior artery circulation were randomly assigned to .The HERMES trial is an international, multicentre, parallel group, randomized, double-blind, study in patients with HFpEF and HFmrEF, evaluating the effect of ziltivekimab 15mg compared with placebo, given once a month, in addition to standard care, on the primary composite outcome of time to first occurrence of cardiovascular death, heart .The study investigators established the Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials (HERMES) collaboration to undertake meta-analysis of pooled individual patient data.Goyal M, Menon BK, van Zwam WH, et al; HERMES Collaborators. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials.
In this trial, endovascular thrombectomy for ischemic stroke 6 to 16 hours after a patient was last known to be well plus standard medical therapy resulted in better 90-day functional outcomes . We performed a prospective, randomized, open-label, adaptive, international trial involving patients with stroke due to occlusion of the internal carotid artery or the first segment of the middle.Michael D Hill, Tudor G Jovin, for the HERMES collaborators Summary Background In 2015, fi ve randomised trials showed effi cacy of endovascular thrombectomy over standard medical care in patients with acute ischaemic stroke caused by . We analyzed data from the highly effective reperfusion evaluated in multiple endovascular stroke trials (HERMES) collaboration, which performed an individual patient data meta‐analysis of 7 randomized controlled trials conducted between 2010 and 2017 assessing the benefit of EVT compared to medical management in patients with anterior .
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hermes trial|large core stroke trials
